A decade after escaping the horrors of Woodsboro, Sidney Prescott returns for a book tour marking her triumph over trauma. Yet, her arrival coincides with the 15th anniversary of the first Ghostface murders, sparking a new wave of killings. Ghostface targets high school students Jenny and Marnie, whose deaths mark the beginning of a brutal spree. Sheriff Dewey Riley investigates while his wife, Gale, tries to relive her glory days by joining the hunt for the killer. The new killings center around Sidney’s cousin, Jill Roberts, and her friends Kirby, Olivia, and Trevor. Ghostface relentlessly stalks the group, leaving a trail of bloodshed that parallels the original murders. As the town falls into chaos, secrets unravel, and Sidney becomes the killer’s ultimate target once again. The shocking climax reveals Jill and her accomplice, Charlie, as the masterminds behind the murders. Consumed by jealousy and a thirst for fame, Jill seeks to frame others and become the sole survivor of her own massacre. However, Sidney confronts her in a brutal hospital showdown, ensuring that the original hero triumphs over her twisted cousin. While Scream 4 initially received mixed reviews, it was praised for its sharp critique of remakes and revitalization of the series after the lackluster reception of Scream 3. Though discussions of a sequel have persisted, the passing of director Wes Craven has cast doubt on the series' continuation.